Structural dynamics and permeability of the TRPV3 pentamer

Abstract TRPV3 belongs to the large superfamily of tetrameric transient receptor potential (TRP) ion channels. Recently, using high-speed atomic force microscopy (HS-AFM), we discovered a rare and transient pentameric state for TRPV3 that is in equilibrium with the tetrameric state, and, using cryo-...

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Bibliographic Details
Main Authors: Shifra Lansky, Zhaokun Wang, Oliver B. Clarke, Christophe Chipot, Simon Scheuring
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59798-9
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