Kinin B<sub>1</sub> Receptor Agonist Enhances Blood-Brain Barrier Permeability in Healthy and Glioblastoma Environments

Kinin B<sub>1</sub> Receptor Agonist Enhances Blood-Brain Barrier Permeability in Healthy and Glioblastoma Environments

<b>Background/Objectives</b>: The low permeability of the blood-brain barrier (BBB) represents a significant challenge to effective systemic chemotherapy for primary and metastatic brain cancers. Kinin receptors play a crucial role in modulating BBB permeability, and their agonist analog...

Full description

Saved in:
Bibliographic Details
Main Authors: Carolina Batista, João Victor Roza Cruz, Michele Siqueira, João Bosco Pesquero, Joice Stipursky, Fabio de Almeida Mendes
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Pharmaceuticals
Subjects:
kinin B<sub>1</sub> receptor
des-Arg<sup>9</sup>-bradykinin
blood-brain barrier
endothelial cells
glioblastoma
Online Access:https://www.mdpi.com/1424-8247/18/4/591
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/1424-8247/18/4/591

Similar Items