Coprecipitation Method of Synthesis, Characterization, and Cytotoxicity of Pr3+:LaF3 (CPr = 3, 7, 12, 20, 30%) Nanoparticles

The Pr3+:LaF3 (CPr = 3, 7, 12, 20, 30%) nanoparticles were characterized by means of high-resolution transmission electron microscopy, X-ray diffraction, optical spectroscopy, energy dispersive X-ray spectroscopy, dynamic light scattering, and MTT assay. It was revealed that the average diameter of...

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Main Authors: Maksim S. Pudovkin, Pavel V. Zelenikhin, Victoria Shtyreva, Oleg A. Morozov, Darya A. Koryakovtseva, Vitaly V. Pavlov, Yury N. Osin, Vladimir G. Evtugyn, Albert A. Akhmadeev, Alexey S. Nizamutdinov, Vadim V. Semashko
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Nanotechnology
Online Access:http://dx.doi.org/10.1155/2018/8516498
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author Maksim S. Pudovkin
Pavel V. Zelenikhin
Victoria Shtyreva
Oleg A. Morozov
Darya A. Koryakovtseva
Vitaly V. Pavlov
Yury N. Osin
Vladimir G. Evtugyn
Albert A. Akhmadeev
Alexey S. Nizamutdinov
Vadim V. Semashko
author_facet Maksim S. Pudovkin
Pavel V. Zelenikhin
Victoria Shtyreva
Oleg A. Morozov
Darya A. Koryakovtseva
Vitaly V. Pavlov
Yury N. Osin
Vladimir G. Evtugyn
Albert A. Akhmadeev
Alexey S. Nizamutdinov
Vadim V. Semashko
author_sort Maksim S. Pudovkin
collection DOAJ
description The Pr3+:LaF3 (CPr = 3, 7, 12, 20, 30%) nanoparticles were characterized by means of high-resolution transmission electron microscopy, X-ray diffraction, optical spectroscopy, energy dispersive X-ray spectroscopy, dynamic light scattering, and MTT assay. It was revealed that the average diameter of all the NPs is around 14–18 nm. The hydrodynamic radius of the Pr3+:LaF3 (CPr = 7%) nanoparticles strongly depends on the medium. It was revealed that hydrodynamic radii of the Pr3+:LaF3 (CPr = 7%) nanoparticles in water, DMEM, and RPMI-1640 biological mediums were 18 ± 5, 41 ± 6, and 186 ± 8 nm, respectively. The Pr3+:LaF3 (CPr = 7%) nanoparticles were nontoxic at micromolar concentrations toward COLO-320 cell line. The lifetime curves were fitted biexponentially, and for the Pr3+:LaF3 (CPr = 7%) NPs, the luminescence lifetimes of Pr3+ ions were 480 ± 2 and 53 ± 5 nanosec.
format Article
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institution Kabale University
issn 1687-9503
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language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Journal of Nanotechnology
spelling doaj-art-6f87ec947c054f0e9acf86cddef267332025-02-03T06:01:13ZengWileyJournal of Nanotechnology1687-95031687-95112018-01-01201810.1155/2018/85164988516498Coprecipitation Method of Synthesis, Characterization, and Cytotoxicity of Pr3+:LaF3 (CPr = 3, 7, 12, 20, 30%) NanoparticlesMaksim S. Pudovkin0Pavel V. Zelenikhin1Victoria Shtyreva2Oleg A. Morozov3Darya A. Koryakovtseva4Vitaly V. Pavlov5Yury N. Osin6Vladimir G. Evtugyn7Albert A. Akhmadeev8Alexey S. Nizamutdinov9Vadim V. Semashko10Kazan Federal University, Kazan, Tatarstan 420008, RussiaKazan Federal University, Kazan, Tatarstan 420008, RussiaKazan Federal University, Kazan, Tatarstan 420008, RussiaKazan Federal University, Kazan, Tatarstan 420008, RussiaKazan Federal University, Kazan, Tatarstan 420008, RussiaKazan Federal University, Kazan, Tatarstan 420008, RussiaKazan Federal University, Kazan, Tatarstan 420008, RussiaKazan Federal University, Kazan, Tatarstan 420008, RussiaKazan Federal University, Kazan, Tatarstan 420008, RussiaKazan Federal University, Kazan, Tatarstan 420008, RussiaKazan Federal University, Kazan, Tatarstan 420008, RussiaThe Pr3+:LaF3 (CPr = 3, 7, 12, 20, 30%) nanoparticles were characterized by means of high-resolution transmission electron microscopy, X-ray diffraction, optical spectroscopy, energy dispersive X-ray spectroscopy, dynamic light scattering, and MTT assay. It was revealed that the average diameter of all the NPs is around 14–18 nm. The hydrodynamic radius of the Pr3+:LaF3 (CPr = 7%) nanoparticles strongly depends on the medium. It was revealed that hydrodynamic radii of the Pr3+:LaF3 (CPr = 7%) nanoparticles in water, DMEM, and RPMI-1640 biological mediums were 18 ± 5, 41 ± 6, and 186 ± 8 nm, respectively. The Pr3+:LaF3 (CPr = 7%) nanoparticles were nontoxic at micromolar concentrations toward COLO-320 cell line. The lifetime curves were fitted biexponentially, and for the Pr3+:LaF3 (CPr = 7%) NPs, the luminescence lifetimes of Pr3+ ions were 480 ± 2 and 53 ± 5 nanosec.http://dx.doi.org/10.1155/2018/8516498
spellingShingle Maksim S. Pudovkin
Pavel V. Zelenikhin
Victoria Shtyreva
Oleg A. Morozov
Darya A. Koryakovtseva
Vitaly V. Pavlov
Yury N. Osin
Vladimir G. Evtugyn
Albert A. Akhmadeev
Alexey S. Nizamutdinov
Vadim V. Semashko
Coprecipitation Method of Synthesis, Characterization, and Cytotoxicity of Pr3+:LaF3 (CPr = 3, 7, 12, 20, 30%) Nanoparticles
Journal of Nanotechnology
title Coprecipitation Method of Synthesis, Characterization, and Cytotoxicity of Pr3+:LaF3 (CPr = 3, 7, 12, 20, 30%) Nanoparticles
title_full Coprecipitation Method of Synthesis, Characterization, and Cytotoxicity of Pr3+:LaF3 (CPr = 3, 7, 12, 20, 30%) Nanoparticles
title_fullStr Coprecipitation Method of Synthesis, Characterization, and Cytotoxicity of Pr3+:LaF3 (CPr = 3, 7, 12, 20, 30%) Nanoparticles
title_full_unstemmed Coprecipitation Method of Synthesis, Characterization, and Cytotoxicity of Pr3+:LaF3 (CPr = 3, 7, 12, 20, 30%) Nanoparticles
title_short Coprecipitation Method of Synthesis, Characterization, and Cytotoxicity of Pr3+:LaF3 (CPr = 3, 7, 12, 20, 30%) Nanoparticles
title_sort coprecipitation method of synthesis characterization and cytotoxicity of pr3 laf3 cpr 3 7 12 20 30 nanoparticles
url http://dx.doi.org/10.1155/2018/8516498
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