Germline genetic scores associated with cancer gene expression and immune responses across multiple cancer types
Abstract Background Cancer is a polygenic disease that involves the dysregulation of multiple biological events, including aberrant cell proliferation and evasion of immune responses, which collectively contribute to cancer development and progression. Although the polygenic risk score (PRS) has ena...
Saved in:
| Main Authors: | Soojin Cha, Injeong Shim, Sang-Hyuk Jung, Beomsu Kim, Soyeon Kim, Mi-So Park, Hyunbin Cho, Yonghyun Nam, Woong-Yang Park, Dokyoon Kim, Hong-Hee Won |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Communications Medicine |
| Online Access: | https://doi.org/10.1038/s43856-025-00958-9 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Identification of a disease-associated germline mutation (A64T) of the ring finger protein 186 gene (RNF186) in Korean patients with ulcerative colitis
by: Sang-Hun Park, et al.
Published: (2025-07-01) -
Serial next-generation sequencing for detecting germline predisposition in acute myeloid leukemia
by: Jae-Sook Ahn, et al.
Published: (2025-07-01) -
Adult onset cryopyrin-associated periodic syndrome due to germline missense mutation in NLRP3 in a previously healthy middle-aged woman
by: Sung Ik Cho, et al.
Published: (2025-08-01) -
Cross-ancestry genome-wide association study identifies implications of SORL1 in cerebral beta-amyloid deposition
by: Jun Pyo Kim, et al.
Published: (2025-04-01) -
Incidence of solid cancers among residents near nuclear facilities: a systematic review and meta-analysis
by: Ga Bin Lee, et al.
Published: (2025-05-01)