Germline genetic scores associated with cancer gene expression and immune responses across multiple cancer types

Abstract Background Cancer is a polygenic disease that involves the dysregulation of multiple biological events, including aberrant cell proliferation and evasion of immune responses, which collectively contribute to cancer development and progression. Although the polygenic risk score (PRS) has ena...

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Bibliographic Details
Main Authors: Soojin Cha, Injeong Shim, Sang-Hyuk Jung, Beomsu Kim, Soyeon Kim, Mi-So Park, Hyunbin Cho, Yonghyun Nam, Woong-Yang Park, Dokyoon Kim, Hong-Hee Won
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-00958-9
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