Emerging highly pathogenic H5N1 influenza triggers fibrotic remodeling in human airway organoids

Emerging highly pathogenic H5N1 influenza triggers fibrotic remodeling in human airway organoids

The ongoing outbreak of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b has affected at least 989 dairy herds across 17 states in the United States (U.S.) and resulted in 70 confirmed human infections, underscoring the urgent need to understand the pathogenesis and therapeutic intervent...

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Bibliographic Details
Main Authors: Hussin Rothan, Ahmed Mostafa, Mahmoud Bayoumi, Chengjin Ye, Ramya S. Barre, Anna Allué-Guardia, Aitor Nogales, Jordi B. Torrelles, Luis Martinez-Sobrido
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Emerging Microbes and Infections
Subjects:
Human airway organoids
influenza virus
prolonged infection
fibrogenesis
ROCK signalling pathway
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2025.2532684
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https://www.tandfonline.com/doi/10.1080/22221751.2025.2532684

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