Advances in Endoscopic Ultrasound in Pancreatic Cancer Screening, Diagnosis, and Palliative Care
Pancreatic cancer is a highly aggressive malignancy with a profoundly poor prognosis. Clinically, the condition most frequently manifests with symptoms including painless jaundice, abdominal discomfort, and back pain. Early diagnosis and the implementation of effective therapeutic strategies are cri...
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MDPI AG
2024-12-01
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| author | Wenyu Zhang Jingzheng Chen Wei Zhang Min Xu |
| author_facet | Wenyu Zhang Jingzheng Chen Wei Zhang Min Xu |
| author_sort | Wenyu Zhang |
| collection | DOAJ |
| description | Pancreatic cancer is a highly aggressive malignancy with a profoundly poor prognosis. Clinically, the condition most frequently manifests with symptoms including painless jaundice, abdominal discomfort, and back pain. Early diagnosis and the implementation of effective therapeutic strategies are critical for improving patient survival outcomes. However, merely 10–20% of patients are diagnosed at an early stage, with the majority presenting at advanced stages, often with metastasis. Consequently, early detection and intervention are crucial for enhancing prognosis. The widespread adoption of endoscopic ultrasonography (EUS) technology in recent years has significantly enhanced the diagnostic accuracy for pancreatic space-occupying lesions. EUS is increasingly recognized for its pivotal role in alleviating malignant biliary obstruction (MBO), gastric outlet obstruction (GOO), and refractory pain in advanced pancreatic cancer. This article aims to provide an overall review of the current applications of EUS in the diagnosis and treatment of pancreatic cancer, exploring its advantages and limitations in early screening, diagnosis, and palliative care. Furthermore, this review explores potential future directions in the field, aiming to provide valuable insights to inform and enhance the clinical management of pancreatic cancer. |
| format | Article |
| id | doaj-art-6f524384cc3149229e3e1aad8ffce1d7 |
| institution | Kabale University |
| issn | 2227-9059 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj-art-6f524384cc3149229e3e1aad8ffce1d72025-01-24T13:23:56ZengMDPI AGBiomedicines2227-90592024-12-011317610.3390/biomedicines13010076Advances in Endoscopic Ultrasound in Pancreatic Cancer Screening, Diagnosis, and Palliative CareWenyu Zhang0Jingzheng Chen1Wei Zhang2Min Xu3Department of Gastroenterology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, ChinaDepartment of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, ChinaDepartment of Gastroenterology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, ChinaDepartment of Gastroenterology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, ChinaPancreatic cancer is a highly aggressive malignancy with a profoundly poor prognosis. Clinically, the condition most frequently manifests with symptoms including painless jaundice, abdominal discomfort, and back pain. Early diagnosis and the implementation of effective therapeutic strategies are critical for improving patient survival outcomes. However, merely 10–20% of patients are diagnosed at an early stage, with the majority presenting at advanced stages, often with metastasis. Consequently, early detection and intervention are crucial for enhancing prognosis. The widespread adoption of endoscopic ultrasonography (EUS) technology in recent years has significantly enhanced the diagnostic accuracy for pancreatic space-occupying lesions. EUS is increasingly recognized for its pivotal role in alleviating malignant biliary obstruction (MBO), gastric outlet obstruction (GOO), and refractory pain in advanced pancreatic cancer. This article aims to provide an overall review of the current applications of EUS in the diagnosis and treatment of pancreatic cancer, exploring its advantages and limitations in early screening, diagnosis, and palliative care. Furthermore, this review explores potential future directions in the field, aiming to provide valuable insights to inform and enhance the clinical management of pancreatic cancer.https://www.mdpi.com/2227-9059/13/1/76endoscopic ultrasoundpancreatic cancerearly screeningpalliative carediagnosis |
| spellingShingle | Wenyu Zhang Jingzheng Chen Wei Zhang Min Xu Advances in Endoscopic Ultrasound in Pancreatic Cancer Screening, Diagnosis, and Palliative Care Biomedicines endoscopic ultrasound pancreatic cancer early screening palliative care diagnosis |
| title | Advances in Endoscopic Ultrasound in Pancreatic Cancer Screening, Diagnosis, and Palliative Care |
| title_full | Advances in Endoscopic Ultrasound in Pancreatic Cancer Screening, Diagnosis, and Palliative Care |
| title_fullStr | Advances in Endoscopic Ultrasound in Pancreatic Cancer Screening, Diagnosis, and Palliative Care |
| title_full_unstemmed | Advances in Endoscopic Ultrasound in Pancreatic Cancer Screening, Diagnosis, and Palliative Care |
| title_short | Advances in Endoscopic Ultrasound in Pancreatic Cancer Screening, Diagnosis, and Palliative Care |
| title_sort | advances in endoscopic ultrasound in pancreatic cancer screening diagnosis and palliative care |
| topic | endoscopic ultrasound pancreatic cancer early screening palliative care diagnosis |
| url | https://www.mdpi.com/2227-9059/13/1/76 |
| work_keys_str_mv | AT wenyuzhang advancesinendoscopicultrasoundinpancreaticcancerscreeningdiagnosisandpalliativecare AT jingzhengchen advancesinendoscopicultrasoundinpancreaticcancerscreeningdiagnosisandpalliativecare AT weizhang advancesinendoscopicultrasoundinpancreaticcancerscreeningdiagnosisandpalliativecare AT minxu advancesinendoscopicultrasoundinpancreaticcancerscreeningdiagnosisandpalliativecare |