Stage-dependent proteomic alterations in aqueous humor of diabetic retinopathy patients based on data-independent acquisition and parallel reaction monitoring

Stage-dependent proteomic alterations in aqueous humor of diabetic retinopathy patients based on data-independent acquisition and parallel reaction monitoring

Abstract Background Diabetic retinopathy (DR), a microvascular complication of diabetes mellitus (DM), represents the predominant cause of preventable vision loss in working-age populations globally. While the pathophysiological mechanisms underlying DR progression remain incompletely understood, ou...

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Main Authors: Yeanqi Jin, Junbin Liu, Xueli Zhang, Liang Zhang, Ying Cui, Xiaoyang Luo, Haoxian Zhu, Zhifan Chen, Mengya Liu, Xiyu Wu, Xinyu Chen, Shuoxin Liao, Guanrong Wu, Xiang Fang, Qianli Meng
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Translational Medicine
Subjects:
Diabetic retinopathy
Aqueous humor
Proteomics
Data-independent acquisition
Parallel reaction monitoring
Online Access:https://doi.org/10.1186/s12967-025-06452-z
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https://doi.org/10.1186/s12967-025-06452-z

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