Barriers in Healthcare to the Use of Optical Coherence Tomography Angiography in Multiple Sclerosis

Abstract Optical coherence tomography angiography (OCT-A) is a state-of-the-art imaging technique for the retinal vasculature to accurately segment the capillary network and assign it to retinal layers. OCT-A is a promising technique to better understand neurological diseases with visual system mani...

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Main Authors: Lukas G. Reeß, Hadi Salih, Murat Delikaya, Friedemann Paul, Frederike Cosima Oertel
Format: Article
Language:English
Published: Adis, Springer Healthcare 2024-11-01
Series:Neurology and Therapy
Subjects:
Online Access:https://doi.org/10.1007/s40120-024-00670-1
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author Lukas G. Reeß
Hadi Salih
Murat Delikaya
Friedemann Paul
Frederike Cosima Oertel
author_facet Lukas G. Reeß
Hadi Salih
Murat Delikaya
Friedemann Paul
Frederike Cosima Oertel
author_sort Lukas G. Reeß
collection DOAJ
description Abstract Optical coherence tomography angiography (OCT-A) is a state-of-the-art imaging technique for the retinal vasculature to accurately segment the capillary network and assign it to retinal layers. OCT-A is a promising technique to better understand neurological diseases with visual system manifestations, such as multiple sclerosis (MS), and to identify and characterize vascular biomarkers. Initial studies suggested vascular changes in MS and its differential diagnoses such as myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) and neuromyelitis optica spectrum disorder (NMOSD). Here we review clinical and technical aspects of OCT-A imaging and discuss the potential for the MS field as well as barriers that need to be overcome before OCT-A can be established in clinical application.
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series Neurology and Therapy
spelling doaj-art-6f2409faa9304ced9f71d1a50a383f3d2025-01-26T12:58:43ZengAdis, Springer HealthcareNeurology and Therapy2193-82532193-65362024-11-01141455610.1007/s40120-024-00670-1Barriers in Healthcare to the Use of Optical Coherence Tomography Angiography in Multiple SclerosisLukas G. Reeß0Hadi Salih1Murat Delikaya2Friedemann Paul3Frederike Cosima Oertel4Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu BerlinExperimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu BerlinExperimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu BerlinExperimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu BerlinExperimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu BerlinAbstract Optical coherence tomography angiography (OCT-A) is a state-of-the-art imaging technique for the retinal vasculature to accurately segment the capillary network and assign it to retinal layers. OCT-A is a promising technique to better understand neurological diseases with visual system manifestations, such as multiple sclerosis (MS), and to identify and characterize vascular biomarkers. Initial studies suggested vascular changes in MS and its differential diagnoses such as myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) and neuromyelitis optica spectrum disorder (NMOSD). Here we review clinical and technical aspects of OCT-A imaging and discuss the potential for the MS field as well as barriers that need to be overcome before OCT-A can be established in clinical application.https://doi.org/10.1007/s40120-024-00670-1Barriers in healthcareClinical applicationMultiple sclerosisOptical coherence tomography angiography
spellingShingle Lukas G. Reeß
Hadi Salih
Murat Delikaya
Friedemann Paul
Frederike Cosima Oertel
Barriers in Healthcare to the Use of Optical Coherence Tomography Angiography in Multiple Sclerosis
Neurology and Therapy
Barriers in healthcare
Clinical application
Multiple sclerosis
Optical coherence tomography angiography
title Barriers in Healthcare to the Use of Optical Coherence Tomography Angiography in Multiple Sclerosis
title_full Barriers in Healthcare to the Use of Optical Coherence Tomography Angiography in Multiple Sclerosis
title_fullStr Barriers in Healthcare to the Use of Optical Coherence Tomography Angiography in Multiple Sclerosis
title_full_unstemmed Barriers in Healthcare to the Use of Optical Coherence Tomography Angiography in Multiple Sclerosis
title_short Barriers in Healthcare to the Use of Optical Coherence Tomography Angiography in Multiple Sclerosis
title_sort barriers in healthcare to the use of optical coherence tomography angiography in multiple sclerosis
topic Barriers in healthcare
Clinical application
Multiple sclerosis
Optical coherence tomography angiography
url https://doi.org/10.1007/s40120-024-00670-1
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