Combined TLR2/TLR4 activation equip non-mucosal dendritic cells to prime Th1 cells with gut tropism

Combined TLR2/TLR4 activation equip non-mucosal dendritic cells to prime Th1 cells with gut tropism

Summary: Activated CD4+ T cells located at mucosal surfaces orchestrate local effector immune mechanisms. When properly polarized, these cells contribute to block infections at early stages and may be essential to restrain the local growth of mucosal tumors, playing a critical role in host protectio...

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Bibliographic Details
Main Authors: Sara Zúquete, Mariana Ferreira, Inês L.S. Delgado, Paula Gazalle, Stephanie Andaluz, Maria Teresa Rosa, Ana Catarina Mendes, Dulce Santos, Sofia Nolasco, Luís Graça, Alexandre Leitão, Afonso P. Basto
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
Subjects:
natural sciences
biological sciences
immunology
immune system
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422402457X
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