A hollow TFG condensate spatially compartmentalizes the early secretory pathway

A hollow TFG condensate spatially compartmentalizes the early secretory pathway

Abstract In the early secretory pathway, endoplasmic reticulum (ER) and Golgi membranes form a nearly spherical interface. In this ribosome-excluding zone, bidirectional transport of cargo coincides with a spatial segregation of anterograde and retrograde carriers by an unknown mechanism. We show th...

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Bibliographic Details
Main Authors: Savannah M. Bogus, William R. Wegeng, Miguel Ruiz, Sindy R. Chavez, Samantha N. Cheung, Khalid S. M. Noori, Ingrid R. Niesman, Andreas M. Ernst
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59118-1
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https://doi.org/10.1038/s41467-025-59118-1

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