TLR4 Agonist and Hypoxia Synergistically Promote the Formation of TLR4/NF-κB/HIF-1α Loop in Human Epithelial Ovarian Cancer

Inflammation and hypoxia are involved in numerous cancer progressions. Reportedly, the toll-like receptor 4 (TLR4)/nuclear factor kappa B (NF-κB) pathway and hypoxia-inducible factor-1α (HIF-1α) are activated and closely related to the chemoresistance and poor prognosis of epithelial ovarian cancer...

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Bibliographic Details
Main Authors: Bin Zhao, Xiulong Niu, Suhui Huang, Jing Yang, Yiyi Wei, Xiujuan Wang, Junhong Wang, Yue Wang, Xiaoqin Guo
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/2022/4201262
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