XBP1 promotes endometrial fibrosis through cGAS-STING signaling pathway in intrauterine adhesion

XBP1 promotes endometrial fibrosis through cGAS-STING signaling pathway in intrauterine adhesion

Abstract Intrauterine adhesion (IUA) was characterized by endometrial fibrosis, leading primarily to hypomenorrhea, infertility and recurrent miscarriage. Epithelial-mesenchymal transition (EMT) is now recognized as a key factor in the development of endometrial fibrosis. X-box binding protein 1 (XB...

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Bibliographic Details
Main Authors: Xixi Wu, Li He, Yonghong Lin, Yunfeng Zheng, Peng Jiang, Chenfan Tian, Ran Mao, Bo Yang, Yuanling Shi, Huisheng Ge, Jianguo Hu, Rui Yuan
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
XBP1
Epithelial-mesenchymal transformation (EMT)
cGAS-STING
Mitochondria DNA (mtDNA)
Intrauterine adhesion (IUA)
Online Access:https://doi.org/10.1038/s41598-025-06162-y
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https://doi.org/10.1038/s41598-025-06162-y

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