Cas3 of type I-Fa CRISPR-Cas system upregulates bacterial biofilm formation and virulence in Acinetobacter baumannii

Abstract Acinetobacter baumannii (A. baumannii) is an important pathogen causing various nosocomial infections. CRISPR-Cas system is the adaptive immune system of bacteria, which is also closely related to the drug resistance and virulence of bacteria. However, the effect and mechanism of cas3 (type...

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Bibliographic Details
Main Authors: Tingting Guo, Jie Yang, Na Zhou, Xiaoli Sun, Changchao Huan, Tao Lin, Guangyu Bao, Jian Hu, Guocai Li
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08124-6
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