Is Anlotinib and Radiotherapy Combination Effective for Non-Small-Cell Lung Cancer with Brain Metastases? A Systematic Scoping Review and Meta-Analysis

Is Anlotinib and Radiotherapy Combination Effective for Non-Small-Cell Lung Cancer with Brain Metastases? A Systematic Scoping Review and Meta-Analysis

<b>Background/Objectives</b>: Non-small-cell lung cancer (NSCLC) frequently metastasizes to the brain, significantly impacting patient prognosis and quality of life. Anlotinib, a novel tyrosine kinase inhibitor, has shown promise in treating NSCLC with brain metastasis. So, we aimed to e...

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Main Authors: Helal F. Hetta, Mostafa A. Sayed Ali, Saleh F. Alqifari, Hoda A. Salem, Khulood A. Qasem, Fawaz E. Alanazi, Amirah Alhowiti, Amirah M. Alatawi, Hyder Mirghani, Tariq Alrasheed, Salwa Q. Bukhari, Khalid A. Almazyad, Sultan A. Alhumaid, Noura H. Abd Ellah, Hashim M. Aljohani, Yasmin N. Ramadan, Reem Sayad
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Pharmaceuticals
Subjects:
anlotinib
novel multi-targeting tyrosine kinase inhibitor
combined non-small-cell lung cancer
NSCLC
brain metastasis
radiotherapy
Online Access:https://www.mdpi.com/1424-8247/18/7/974
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