Mechanism of LINC01018/miR-182-5p/Rab27B in the immune escape through PD-L1-mediated CD8+ T cell suppression in glioma

Mechanism of LINC01018/miR-182-5p/Rab27B in the immune escape through PD-L1-mediated CD8+ T cell suppression in glioma

Abstract Background Glioma is a malignant tumor associated with poorer prognosis. This study aims to elucidate the mechanism of LINC01018/miR-182-5p/Rab27B axis in PD-L1-mediated CD8+ T cell suppression in the progression of gliomas. Methods LINC01018, miR-182-5p, and Rab27B expression levels in gli...

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Bibliographic Details
Main Authors: Su Hu, Guoshuo Chen, Aiping Luo, Hailin Zhao, Dan Li, Biao Peng, Jike Du, Dongdong Luo
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Biology Direct
Subjects:
Glioma
Immune escape
LINC01018
miR-182-5p
Rab27B
EVs
Online Access:https://doi.org/10.1186/s13062-025-00651-w
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https://doi.org/10.1186/s13062-025-00651-w

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