pH homeostasis links the nutrient sensing PKA/TORC1/Sch9 ménage-à-trois to stress tolerance and longevity

pH homeostasis links the nutrient sensing PKA/TORC1/Sch9 ménage-à-trois to stress tolerance and longevity

The plasma membrane H+-ATPase Pma1 and the vacuolar V-ATPase act in close harmony to tightly control pH homeostasis, which is essential for a vast number of physiological processes. As these main two regulators of pH are responsive to the nutritional status of the cell, it seems evident that pH home...

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Bibliographic Details
Main Authors: Marie-Anne Deprez, Elja Eskes, Tobias Wilms, Paula Ludovico, Joris Winderickx
Format: Article
Language:English
Published: Shared Science Publishers OG 2018-01-01
Series:Microbial Cell
Subjects:
yeast
ageing
longevity
pH
V-ATPase
Pma1
PKA
TORC1
Sch9
Online Access:http://microbialcell.com/researcharticles/ph-homeostasis-links-the-nutrient-sensing-pka-torc1-sch9-menage-a-trois-to-stress-tolerance-and-longevity/
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http://microbialcell.com/researcharticles/ph-homeostasis-links-the-nutrient-sensing-pka-torc1-sch9-menage-a-trois-to-stress-tolerance-and-longevity/

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