Chitosan-Based Nanoparticles for Intracellular Delivery of ISAV Fusion Protein cDNA into Melanoma Cells: A Path to Develop Oncolytic Anticancer Therapies

Chitosan-Based Nanoparticles for Intracellular Delivery of ISAV Fusion Protein cDNA into Melanoma Cells: A Path to Develop Oncolytic Anticancer Therapies

Oncolytic virus therapy has been tested against cancer in preclinical models and clinical assays. Current evidence shows that viruses induce cytopathic effects associated with fusogenic protein-mediated syncytium formation and immunogenic cell death of eukaryotic cells. We have previously demonstrat...

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Main Authors: Claudia Robles-Planells, Giselle Sánchez-Guerrero, Carlos Barrera-Avalos, Silvia Matiacevich, Leonel E. Rojo, Jorge Pavez, Edison Salas-Huenuleo, Marcelo J. Kogan, Alejandro Escobar, Luis A. Milla, Ricardo Fernandez, Mónica Imarai, Eugenio Spencer, Juan Pablo Huidobro-Toro, Claudio Acuña-Castillo
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2020/8680692
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http://dx.doi.org/10.1155/2020/8680692

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