Gammaherpesvirus infection triggers the formation of tRNA fragments from premature tRNAs

Gammaherpesvirus infection triggers the formation of tRNA fragments from premature tRNAs

ABSTRACT Transfer RNAs (tRNAs) are fundamental for both cellular and viral gene expression during viral infection. In addition, mounting evidence supports the biological function for tRNA cleavage products, including the control of gene expression during conditions of stress and infection. We previo...

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Main Authors: Aidan C. Manning, Mahmoud M. Bashir, Kyle Rapchak, Calyssa J. Huff, Ariana R. Jimenez, Sheila Gonzalez, Courtney L. Woodruff, Heather E. Upton, Kathleen Collins, Todd M. Lowe, Jessica M. Tucker
Format: Article
Language:English
Published: American Society for Microbiology 2025-07-01
Series:mBio
Subjects:
virology
herpesviruses
tRNA
tRNA fragments
tRNA splicing
viral tRNA
Online Access:https://journals.asm.org/doi/10.1128/mbio.00875-25
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https://journals.asm.org/doi/10.1128/mbio.00875-25

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