Synthesis of chiral germanium center enabled by poly-deborylative alkylation and desymmetrization

Abstract Chiral germanium centers are historically undervalued due to their extremely limited synthetic accessibility. Although germanium shares similar chemical properties with silicon, synthesizing chiral germanium centers proves significantly more challenging. To facilitate rapid access to chiral...

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Bibliographic Details
Main Authors: Ke Wang, Xin-Yuan Liu, Zhe Dong
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60397-x
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