Correction of Batch Effect in Gut Microbiota Profiling of ASD Cohorts from Different Geographical Origins

Correction of Batch Effect in Gut Microbiota Profiling of ASD Cohorts from Different Geographical Origins

Background: To date, there have been numerous metataxonomic studies on gut microbiota (GM) profiling based on the analyses of data from public repositories. However, differences in study population and wet and dry pipelines have produced discordant results. Herein, we propose a biostatistical approa...

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Bibliographic Details
Main Authors: Matteo Scanu, Federica Del Chierico, Riccardo Marsiglia, Francesca Toto, Silvia Guerrera, Giovanni Valeri, Stefano Vicari, Lorenza Putignani
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Biomedicines
Subjects:
machine learning
batch effect normalization
quantile regression
autism spectrum disorders (ASDs)
gut microbiota
intestinal biomarkers
Online Access:https://www.mdpi.com/2227-9059/12/10/2350
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