Determinants of functional cure in interferon-treated chronic hepatitis B: a retrospective cohort analysis of HBsAg dynamics and clinical predictors

Background and ObjectivesFunctional cure of chronic hepatitis B (CHB) is the optimal goal of antiviral therapy. This study evaluates the functional cure rates in a large cohort treated with interferon (IFNα) and explores baseline predictors to optimize personalized treatment strategies.MethodsThis r...

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Bibliographic Details
Main Authors: Daqiong Zhou, Jianru Jia, Feng Zhao, Jiangyu Liu, Zichen Zhang, Zhenhuan Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cellular and Infection Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1615327/full
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