The liver pharmacological and xenobiotic gene response repertoire

The liver pharmacological and xenobiotic gene response repertoire

Abstract We have used a supervised classification approach to systematically mine a large microarray database derived from livers of compound‐treated rats. Thirty‐four distinct signatures (classifiers) for pharmacological and toxicological end points can be identified. Just 200 genes are sufficient...

Full description

Saved in:
Bibliographic Details
Main Authors: Georges Natsoulis, Cecelia I Pearson, Jeremy Gollub, Barrett P Eynon, Joe Ferng, Ramesh Nair, Radha Idury, May D Lee, Mark R Fielden, Richard J Brennan, Alan H Roter, Kurt Jarnagin
Format: Article
Language:English
Published: Springer Nature 2008-03-01
Series:Molecular Systems Biology
Subjects:
biomarker
data mining
liver
toxicity
toxicology
xenobiotic
Online Access:https://doi.org/10.1038/msb.2008.9
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/msb.2008.9

Similar Items