DNA methylation models of protein abundance across the lifecourse

DNA methylation models of protein abundance across the lifecourse

Abstract Background Multiple studies have shown that DNA methylation (DNAm) models of protein abundance can be informative about exposure, phenotype and disease risk. Here we investigate and provide descriptive details of the capacity of DNAm to capture non-genetic variation in protein abundance acr...

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Bibliographic Details
Main Authors: Scott Waterfield, Paul Yousefi, Matt Suderman
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Clinical Epigenetics
Subjects:
Epigenetics
DNA methylation
Proteomics
Penalised regression
Lifecourse epidemiology
ALSPAC
Online Access:https://doi.org/10.1186/s13148-024-01802-y
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https://doi.org/10.1186/s13148-024-01802-y

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