AXL in myeloid malignancies – an elusive target?

AXL in myeloid malignancies – an elusive target?

Abstract The TAM receptor tyrosine kinase family member AXL plays critical roles in tissue homeostasis, survival, chemoresistance, and motility. This study investigates the receptor expression in six AML cell lines and bone marrow myeloblasts from 25 patients with myeloid neoplasms. We found that AX...

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Bibliographic Details
Main Authors: Pia Aehnlich, Katharina Leuchte, Claudia Schöllkopf, Sara Fresnillo Salo, Tina J. Seremet, Estrid Høgdall, Özcan Met, Kirsten Grønbaek, Per thor Straten
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Biomarker Research
Subjects:
AXL
Acute myeloid leukemia (AML)
Tumor immunology
TAM receptors
Online Access:https://doi.org/10.1186/s40364-024-00704-8
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https://doi.org/10.1186/s40364-024-00704-8

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