Gremlin-2 is a novel tumor suppressor that negatively regulates ID1 in breast cancer

Gremlin-2 is a novel tumor suppressor that negatively regulates ID1 in breast cancer

Abstract Background Breast cancer is one of the most common cancers in women and is closely associated with obesity. Gremlin-2 (GREM2), an antagonist for bone morphogenetic proteins (BMPs), has been considered an inhibitor of adipogenic differentiation in adipose-derived stromal/stem cells. However,...

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Main Authors: Jiwoo Jung, Na Hui Kim, Jayeon Park, Dayeon Lim, Minji Kwon, World Gil, Suyeon Jung, Minjeong Go, Chaeeon Kim, Ye Hwang Cheong, Mee-Hyun Lee, Hee Sun Park, Yong-Bin Eom, Sin-Aye Park
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Breast Cancer Research
Subjects:
Gremlin-2
Breast cancer
Hypermethylation
RNA sequencing
Inhibitor of DNA-binding-1
Tumor suppressor
Online Access:https://doi.org/10.1186/s13058-024-01935-1
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https://doi.org/10.1186/s13058-024-01935-1

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