Investigating the cytotoxic effect of aqueous extract of Peganum harmala on oxaliplatin-resistant HCT116 cell line and evaluating BAX gene expression

Introduction:  Colorectal cancer is a prevalent digestive tract malignancy, with oxaliplatin being an effective chemotherapeutic drug, but long-term use can lead to drug resistance. It is crucial to develop methods to reduce CRC cells' oxaliplatin resistance. Peganum harmala L. (P. harmala), is...

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Main Authors: Zahra Salimizadeh, Sattar Tahmasebi Enferadi, Tayebeh Majidizadeh, Razieh Jalal, Frouzandeh Mahjoubi
Format: Article
Language:fas
Published: Ilam University of Medical Sciences 2025-03-01
Series:Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām
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Online Access:http://sjimu.medilam.ac.ir/article-1-8413-en.pdf
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