Aberrant encoding of event saliency in the orbitofrontal cortex following loss of the psychiatric-associated circular RNA, circHomer1

Abstract CircHomer1 is an activity-dependent circular RNA (circRNA) isoform produced from back-splicing of the Homer1 transcript. Homer1 isoforms are well-known regulators of homeostatic synaptic plasticity through post-synaptic density scaffold regulation. Homer1 polymorphisms have been associated...

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Bibliographic Details
Main Authors: Amber J. Zimmerman, Jason P. Weick, Grigorios Papageorgiou, Nikolaos Mellios, Jonathan L. Brigman
Format: Article
Language:English
Published: Nature Publishing Group 2024-11-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-024-03188-0
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