Hybrid azole-based conjugates as upcoming anticancer and antimicrobial agents

Hybrid azole-based conjugates as upcoming anticancer and antimicrobial agents

Aim: This study discloses the synthesis and the antimicrobial and anticancer activities of four molecules of structural basis saccharin-thiadiazolyl (4), saccharin-pyridyl (6, 8), and tetrazole-thiadiazolyl (11). Methods: Antimicrobial properties of the molecules were evaluated by the well-diffusion...

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Main Authors: Luís M. T. Frija, Bruno E. C. Guerreiro, Inês C. C. Costa, Vera M. S. Isca, Lucília Saraiva, Beatriz G. Neves, Mariana Magalhães, Célia Cabral, Maria L. S. Cristiano, Patrícia Rijo
Format: Article
Language:English
Published: Open Exploration 2023-11-01
Series:Exploration of Drug Science
Subjects:
1
3
4-thiadiazole
tetrazole
mixed-azoles
antimicrobial activity
glioblastoma
colon adenocarcinoma
breast adenocarcinoma
melanoma
Online Access:https://www.explorationpub.com/uploads/Article/A100828/100828.pdf
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