Design and evaluation of a poly-epitope based vaccine for the induction of influenza A virus cross-reactive CD8 + T cell responses

Abstract The availability of influenza vaccines that can induce broadly protective immune responses is highly desirable and could also mitigate the impact of future influenza pandemics. Ideally, these vaccines also induce virus-specific CD8 + T cells, which have been identified as an independent cor...

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Bibliographic Details
Main Authors: Sharmistha Dam, Alina Tscherne, Leoni Engels, Gerd Sutter, Albert D. M. E. Osterhaus, Guus F. Rimmelzwaan
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-95479-9
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