<i>CYP2C19</i> Genetic Variants and Major Depressive Disorder: A Systematic Review

<i>CYP2C19</i> Genetic Variants and Major Depressive Disorder: A Systematic Review

Major depressive disorder (MDD) affects over 300 million people globally and has a multifactorial etiology. The CYP2C19 enzyme, involved in metabolizing certain antidepressants, can influence treatment response. Following the PRISMA protocol and PECOS strategy, this systematic review assessed the va...

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Main Authors: Larissa Sousa Silva Bonasser, Calliandra Maria de Souza Silva, Caroline Ferreira Fratelli, Bruna Rodrigues Gontijo, Juliana Moura Alves Seixas, Livia Cristina Lira de Sá Barreto, Izabel Cristina Rodrigues da Silva
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Pharmaceuticals
Subjects:
<i>CYP2C19</i>
depressive disorder
major
polymorphism
genetic
Online Access:https://www.mdpi.com/1424-8247/17/11/1461
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