Single cell RNA sequencing reveals the reshaping effect of perfluorooctanoic acid on the intestinal microenvironment of mice

Single cell RNA sequencing reveals the reshaping effect of perfluorooctanoic acid on the intestinal microenvironment of mice

Perfluorooctanoic acid (PFOA), a prevalent perfluorinated compound pollutants, has been implicated in the development of various gastrointestinal disorders. However, the specific PFOA-induced intestinal microenvironment alterations remain poorly characterized. In this study, we established a chronic...

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Bibliographic Details
Main Authors: Ya Gao, Jiayun Guan, Rui Zhou, Zewei Li, Tianyang Chen, Kaican Yang, Rong Huang, Yue Huang, Siting Zheng, Zhenhua Huang, Xiaoxiang Rong
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Perfluorooctanoic acid
Intestinal injury
Single-cell RNA sequencing
Gut microenvironment
Intestinal epithelial cell
T cell
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325008851
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