ERBB4 selectively amplifies TGF-β pro-metastatic responses

ERBB4 selectively amplifies TGF-β pro-metastatic responses

Summary: Transforming growth factor β (TGF-β) is well known to play paradoxical roles in tumorigenesis as it has both growth-inhibitory and pro-metastatic effects. However, the underlying mechanisms of how TGF-β drives the opposing responses remain largely unknown. Here, we report that ERBB4, a memb...

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Main Authors: Peihong Luo, Huanyu Hong, Baoling Zhang, Jie Li, Shuyi Zhang, Chaomin Yue, Jin Cao, Jia Wang, Yuhan Dai, Qingqing Liao, Pinglong Xu, Bing Yang, Xia Liu, Xia Lin, Yi Yu, Xin-Hua Feng
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Cell Reports
Subjects:
CP: Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724015614
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http://www.sciencedirect.com/science/article/pii/S2211124724015614

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