A Data‐Driven Epigenetic Characterization of Morning Fatigue Severity in Oncology Patients Receiving Chemotherapy: Associations With Epigenetic Age Acceleration, Blood Cell Types, and Expression‐Associated Methylation

A Data‐Driven Epigenetic Characterization of Morning Fatigue Severity in Oncology Patients Receiving Chemotherapy: Associations With Epigenetic Age Acceleration, Blood Cell Types, and Expression‐Associated Methylation

ABSTRACT Background Moderate‐to‐severe fatigue commonly occurs in patients with cancer. Given the numerous roles that epigenetic processes may play in the development and severity of fatigue, the purposes of this study were to (1) use a data‐driven discovery approach to evaluate for mechanisms under...

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Main Authors: Caroline Le, Maureen Lewis, Carolyn S. Harris, Liam Berger, Esther Chavez‐Iglesias, Lisa Morse, Anatol Sucher, Ritu Roy, Adam Olshen, Marilyn J. Hammer, Steve Paul, Margaret Wallhagen, Raymond Chan, Michael Sayer, Sue Yom, Nam‐Woo Cho, Alexandre Chan, Jon Levine, Anand Dhruva, Christine Miaskowski, Yvette P. Conley, Kord M. Kober
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Cancer Medicine
Online Access:https://doi.org/10.1002/cam4.71067
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https://doi.org/10.1002/cam4.71067

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