The roles of NHEJ and TLS pathways in genomic alterations and phenotypic evolution in the yeast Yarrowia lipolytica

Abstract Non-homologous end joining (NHEJ) is a DNA repair pathway that directly ligates broken DNA ends without the need for a homologous template, whereas translesion synthesis (TLS) is a DNA damage tolerance mechanism in which specialized DNA polymerases bypass lesions on the template strand. Alt...

Full description

Saved in:
Bibliographic Details
Main Authors: Cen Yan, Ye-Ke Wang, Yuan-Ru Xiong, Xin-Qiu Zhou, Yuan-Chun Fang, Ruo-Tian Nie, Cunqi Ye, Ke Zhang, Dao-Qiong Zheng
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Applied Microbiology and Biotechnology
Subjects:
Online Access:https://doi.org/10.1007/s00253-025-13575-2
Tags: Add Tag
No Tags, Be the first to tag this record!