Caprylic Acid Restores Branched-Chain Amino Acid Metabolism in a Mouse Cachexia Model

Caprylic Acid Restores Branched-Chain Amino Acid Metabolism in a Mouse Cachexia Model

Cancer-associated sarcopenia is closely linked to the prognosis of cancer patients, making its management a critical aspect of cancer treatment. Branched-chain amino acids (BCAAs) are known to promote skeletal muscle growth in healthy individuals; however, their efficacy in cancer patients remains c...

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Main Authors: Isao Kawahara, Rina Fujiwara-Tani, Takuya Mori, Shota Nukaga, Ryoichi Nishida, Yoshihiro Miyagawa, Kei Goto, Hitoshi Ohmori, Kiyomu Fujii, Yi Luo, Takamitsu Sasaki, Chie Nakashima, Ruiko Ogata, Hiroki Kuniyasu
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Current Issues in Molecular Biology
Subjects:
cancer sarcopenia
branched-chain amino acids
branched-chain α-ketoacid dehydrogenase
caprylic acid
Online Access:https://www.mdpi.com/1467-3045/47/5/325
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