A Potential Application of a Piezoelectric Atomiser for Ophthalmic Drug Delivery
A liquid atomiser composed of a piezoelectric transducer and a metal plate with numerous micro-apertures is studied to identify the most influential factors on its atomising performance. The Taguchi method is employed in the experiment design and analysis of the study on how each factor acts in the...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2007-01-01
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| Series: | Applied Bionics and Biomechanics |
| Online Access: | http://dx.doi.org/10.1080/11762320701403906 |
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| _version_ | 1832547642641481728 |
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| author | Wei Xia Hung-Yao Hsu Lingxue Kong Allan Evans Ryan Lee |
| author_facet | Wei Xia Hung-Yao Hsu Lingxue Kong Allan Evans Ryan Lee |
| author_sort | Wei Xia |
| collection | DOAJ |
| description | A liquid atomiser composed of a piezoelectric transducer and a metal plate with numerous micro-apertures is studied to identify the most influential factors on its atomising performance. The Taguchi method is employed in the experiment design and analysis of the study on how each factor acts in the atomising process. An optimal condition is determined for producing a stream of droplets. The study shows that the droplet size and the spraying velocity are suitable for ophthalmic drug delivery application, with an even distribution of the drug over most of the eyeball surface area due to the controllable cross-sectional area of the droplet stream. This greatly improves the treatment effectiveness and efficiency of eye therapy. Finally, a structure of the ophthalmic drug delivery system is proposed. |
| format | Article |
| id | doaj-art-6d243d50804b4f62b946875ab6f5195a |
| institution | Kabale University |
| issn | 1176-2322 1754-2103 |
| language | English |
| publishDate | 2007-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Applied Bionics and Biomechanics |
| spelling | doaj-art-6d243d50804b4f62b946875ab6f5195a2025-02-03T06:43:53ZengWileyApplied Bionics and Biomechanics1176-23221754-21032007-01-014191710.1080/11762320701403906A Potential Application of a Piezoelectric Atomiser for Ophthalmic Drug DeliveryWei Xia0Hung-Yao Hsu1Lingxue Kong2Allan Evans3Ryan Lee4Centre for Material and Fibre Innovation, Deakin University, AustraliaCentre for Material and Fibre Innovation, Deakin University, AustraliaCentre for Material and Fibre Innovation, Deakin University, AustraliaDivision of Health Sciences, University of South Australia, Adelaide, AustraliaSunnytec Electronics Co., Ltd., TaiwanA liquid atomiser composed of a piezoelectric transducer and a metal plate with numerous micro-apertures is studied to identify the most influential factors on its atomising performance. The Taguchi method is employed in the experiment design and analysis of the study on how each factor acts in the atomising process. An optimal condition is determined for producing a stream of droplets. The study shows that the droplet size and the spraying velocity are suitable for ophthalmic drug delivery application, with an even distribution of the drug over most of the eyeball surface area due to the controllable cross-sectional area of the droplet stream. This greatly improves the treatment effectiveness and efficiency of eye therapy. Finally, a structure of the ophthalmic drug delivery system is proposed.http://dx.doi.org/10.1080/11762320701403906 |
| spellingShingle | Wei Xia Hung-Yao Hsu Lingxue Kong Allan Evans Ryan Lee A Potential Application of a Piezoelectric Atomiser for Ophthalmic Drug Delivery Applied Bionics and Biomechanics |
| title | A Potential Application of a Piezoelectric Atomiser for Ophthalmic Drug Delivery |
| title_full | A Potential Application of a Piezoelectric Atomiser for Ophthalmic Drug Delivery |
| title_fullStr | A Potential Application of a Piezoelectric Atomiser for Ophthalmic Drug Delivery |
| title_full_unstemmed | A Potential Application of a Piezoelectric Atomiser for Ophthalmic Drug Delivery |
| title_short | A Potential Application of a Piezoelectric Atomiser for Ophthalmic Drug Delivery |
| title_sort | potential application of a piezoelectric atomiser for ophthalmic drug delivery |
| url | http://dx.doi.org/10.1080/11762320701403906 |
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