Clinical Significance of Autoantibodies to P53 Protein in Patients with Autoimmune Liver Diseases

Mutations in the p53 gene leading to conformational changes in the p53 protein have been well established in many human cancers. Conformational changes and/or cellular accumulation of the protein may induce an immune response, resulting in circulating autoantibodies to p53, which have been documente...

Full description

Saved in:
Bibliographic Details
Main Authors: Takashi Himoto, Hirohito Yoneyama, Kazutaka Kurokohchi, Michio Inukai, Hisashi Masugata, Fuminori Goda, Reiji Haba, Seishiro Watanabe, Shoichi Senda, Tsutomu Masaki
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2012/890698
Tags: Add Tag
No Tags, Be the first to tag this record!