Design, synthesis, and structural investigations of novel (S)-amide derivatives as promising ACE inhibitors

Novel derivatives of potential angiotensin converting enzyme (ACE-I) inhibitors (compounds 5a-e) were synthesized by reacting homophthalic anhydride with methyl esters of L-amino acids (L-isoleucine, L-phenylalanine, L-tyrosine, L-methionine, and L-serine). This reaction resulted in yields of 85% fo...

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Bibliographic Details
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Kuwait Journal of Science
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Online Access:https://www.sciencedirect.com/science/article/pii/S230741082400138X
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