Modeling Stromal Cells Inside the Tumor Microenvironment of Ovarian Cancer: In Vitro Generation of Cancer‐Associated Fibroblast‐Like Cells and Their Impact in a 3D Model

Modeling Stromal Cells Inside the Tumor Microenvironment of Ovarian Cancer: In Vitro Generation of Cancer‐Associated Fibroblast‐Like Cells and Their Impact in a 3D Model

ABSTRACT The tumor microenvironment (TME) is the combination of cells and factors that promotes tumor progression, and cancer‐associated fibroblasts (CAFs) are a key component within TME. CAF originates from various stromal cells and is activated by factors such as transforming growth factor‐beta (T...

Full description

Saved in:
Bibliographic Details
Main Authors: Jacopo Romoli, Paola Chiodelli, Patrizia Bonassi Signoroni, Elsa Vertua, Clarissa Ferrari, Elisabetta Giuzzi, Alice Paini, Elisa Scalvini, Andrea Papait, Francesca Romana Stefani, Antonietta Rosa Silini, Ornella Parolini
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:MedComm
Subjects:
3D model
cancer‐associated fibroblast
ovarian cancer
tumor microenvironment
Online Access:https://doi.org/10.1002/mco2.70172
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1002/mco2.70172

Similar Items