Machine learning uncovers the transcriptional regulatory network for the production host Streptomyces albidoflavus

Machine learning uncovers the transcriptional regulatory network for the production host Streptomyces albidoflavus

Summary: Streptomyces albidoflavus is a widely used strain for natural product discovery and production through heterologous biosynthetic gene clusters (BGCs). However, the transcriptional regulatory network (TRN) and its impact on secondary metabolism remain poorly understood. Here, we characterize...

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Bibliographic Details
Main Authors: Mathias Jönsson, Renata Sigrist, Tetiana Gren, Mykhaylo Semenov Petrov, Nils Emil Junge Marcussen, Anna Svetlova, Pep Charusanti, Peter Gockel, Bernhard O. Palsson, Lei Yang, Emre Özdemir
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Cell Reports
Subjects:
CP: Microbiology
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725001639
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http://www.sciencedirect.com/science/article/pii/S2211124725001639

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