A solid‐phase transfection platform for arrayed CRISPR screens

A solid‐phase transfection platform for arrayed CRISPR screens

Abstract Arrayed CRISPR‐based screens emerge as a powerful alternative to pooled screens making it possible to investigate a wide range of cellular phenotypes that are typically not amenable to pooled screens. Here, we describe a solid‐phase transfection platform that enables CRISPR‐based genetic sc...

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Bibliographic Details
Main Authors: Özdemirhan Serçin, Sabine Reither, Paris Roidos, Nadja Ballin, Spyridon Palikyras, Anna Baginska, Katrin Rein, Maria Llamazares, Aliaksandr Halavatyi, Hauke Winter, Thomas Muley, Renata Z Jurkowska, Amir Abdollahi, Frank T Zenke, Beate Neumann, Balca R Mardin
Format: Article
Language:English
Published: Springer Nature 2019-12-01
Series:Molecular Systems Biology
Subjects:
arrayed screens
CRISPR/Cas9
gRNA/RNP delivery
solid phase
transfection platform
Online Access:https://doi.org/10.15252/msb.20198983
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https://doi.org/10.15252/msb.20198983

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