Comparative study of cytochrome P450 expression in the kidneys of Lepus yarkandensis and Oryctolagus cuniculus

Comparative study of cytochrome P450 expression in the kidneys of Lepus yarkandensis and Oryctolagus cuniculus

Abstract Lepus yarkandensis is a desert hare of the Tarim Basin in western China, and it has strong adaptability to drought environments. Cytochrome P450s (CYP450s) are important metabolic enzymes, and their metabolites (19-hydroxyeicosatetraenoic acid (19-HETE), 20-HETE, and epoxyeicosatrienoic aci...

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Bibliographic Details
Main Authors: Jianping Zhang, Yongle Li, Dingwei Shao, Bing Chao, Guoquan Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Lepus yarkandensis
Cytochrome P450
Kidney
Adaptation
Drought environment
Online Access:https://doi.org/10.1038/s41598-025-91603-x
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https://doi.org/10.1038/s41598-025-91603-x

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