Characterization of a chemically induced osteoarthritis model in zebrafish

Characterization of a chemically induced osteoarthritis model in zebrafish

Abstract Osteoarthritis (OA) is characterized by the progressive degeneration of the synovial joint, leading to irreversible damage to articular cartilage and subchondral bone. While animal models have advanced our understanding of OA, numerous unresolved issues still remain. The zebrafish, known fo...

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Bibliographic Details
Main Authors: Gongyi Xiao, Jin Qin, Huiping Yang, Qizhi Song, Ruobin Zhang, Junlan Huang, Yuexi Mou, Wen Liu, Xianding Sun, Mao Nie
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Osteoarthritis
Zebrafish model
Jaw joint
Mono-iodoacetate
Collagenase type II
Online Access:https://doi.org/10.1038/s41598-025-88125-x
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https://doi.org/10.1038/s41598-025-88125-x

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