Umckalin Promotes Melanogenesis in B16F10 Cells Through the Activation of Wnt/β-Catenin and MAPK Signaling Pathways

Melanogenesis is regulated by melanogenic enzymes such as tyrosinase (TYR), TRP-1, and TRP-2, whose expression is controlled by the microphthalmia-associated transcription factor (MITF). Various signaling pathways, including cAMP/PKA, MAPK/ERK, Wnt/β-catenin, and PI3K/Akt, are involved in this proce...

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Bibliographic Details
Main Authors: So-Yeon Oh, Chang-Gu Hyun
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Applied Biosciences
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Online Access:https://www.mdpi.com/2813-0464/4/2/20
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