Efficacy of an Amphipathic Oligopeptide to Shuttle and Release a cis-Acting DNA Decoy into Human Cells
We investigated the ability of an amphipathic oligopeptide to carry a synthetic ds- DNA oligonucleotide inside human cells. The oligonucleotide was designed as a decoy binding site for the transcriptional activator of the methylguanine-DNA methyltransferase (MGMT) gene. The complex oligopeptide and...
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| Main Authors: | L. Citti, P. Rovero, M.G. Colombo, L. Mariani, L. Poliseno, G. Rainaldi |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2002-01-01
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| Series: | BioTechniques |
| Online Access: | https://www.future-science.com/doi/10.2144/02321dd03 |
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