Efficacy of an Amphipathic Oligopeptide to Shuttle and Release a cis-Acting DNA Decoy into Human Cells

We investigated the ability of an amphipathic oligopeptide to carry a synthetic ds- DNA oligonucleotide inside human cells. The oligonucleotide was designed as a decoy binding site for the transcriptional activator of the methylguanine-DNA methyltransferase (MGMT) gene. The complex oligopeptide and...

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Bibliographic Details
Main Authors: L. Citti, P. Rovero, M.G. Colombo, L. Mariani, L. Poliseno, G. Rainaldi
Format: Article
Language:English
Published: Taylor & Francis Group 2002-01-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/02321dd03
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