Involvement of tdTomato-Tagged RPE cells in a mouse PVR model with enzymatically compromised retina

Involvement of tdTomato-Tagged RPE cells in a mouse PVR model with enzymatically compromised retina

Abstract Ocular trauma and surgery are considered the most common cause for proliferative vitreoretinopathy (PVR). Many retinal cell types are thought to be the cellular source for PVR although most risk factors for PVR are associated with intravitreal dispersion of the retinal pigment epithelium (R...

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Bibliographic Details
Main Authors: Yao Chen, Xiao Liu, Ashwini Kini, John Y. Liu, Xiaoqin Lu, Ling Gao, Henry J. Kaplan, Douglas C. Dean, Yongqing Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Proliferative vitreoretinopathy
Retinal pigment epithelium
Epiretinal membrane
PVR mouse model
RPE cell migration
Online Access:https://doi.org/10.1038/s41598-025-93999-y
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https://doi.org/10.1038/s41598-025-93999-y

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