Clinical importance of eflornithine (α-difluoromethylornithine) for the treatment of malignant gliomas

This review covers the literature between 1989 and 2007 on studies relevant to the neuro-oncology usage of eflornithine (α-difluoromethylornithine), an oral agent that irreversibly inhibits the enzyme ornithine decarboxylase. It covers the use of eflornithine, alone or in combination, to treat high-...

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Bibliographic Details
Main Authors: Victor A Levin, Sandra E Ictech, Kenneth R Hess
Format: Article
Language:English
Published: Taylor & Francis Group 2018-04-01
Series:CNS Oncology
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Online Access:https://www.futuremedicine.com/doi/10.2217/cns-2017-0031
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