Evaluating methods for identifying and quantifying Streptococcus pneumoniae co-colonization using next-generation sequencing data

Evaluating methods for identifying and quantifying Streptococcus pneumoniae co-colonization using next-generation sequencing data

ABSTRACT Detection of multiple pneumococcal serotype carriage can enhance monitoring of pneumococcal vaccine impact, particularly among high-burden childhood populations. We assessed methods for identifying co-carriage of pneumococcal serotypes from whole-genome sequences. Twenty-four nasopharyngeal...

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Main Authors: Jada Hackman, Martin L. Hibberd, Todd D. Swarthout, Jason Hinds, James Ashall, Carmen Sheppard, Gerry Tonkin-Hill, Kate Gould, Comfort Brown, Jacquline Msefula, Andrew A. Mataya, Michiko Toizumi, Lay-Myint Yoshida, Neil French, Robert S. Heyderman, Stefan Flasche, Brenda Kwambana, Stéphane Hué
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:Microbiology Spectrum
Subjects:
co-carriage
pneumococcus
Africa
Streptococcus pneumoniae
sequencing
microarray
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03643-23
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https://journals.asm.org/doi/10.1128/spectrum.03643-23

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